OBJECTIVE: To review the research progress and medical application of nano-materials. METHODS: The literature review and comprehensive analysis, methods were used in this study. RESULTS: The Nanotechnology is a typical crossing knowledge. It could be extensively applied in the fields of novel biomaterials, effective transmission of bioactive factor; the detection of functions for all vital organ systems, vascular circulation condition, the control of repair of burn trauma wounds will be monitored by the varied methods of nano technology combined with molecular biological engineering. CONCLUSION: The application of Nanotechnology will play important roles in clinical medicine, wound repair and basic research for the traditional Chinese medicine.
Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes, which seriously threatens the vision of patients. The pathogenesis of DR is complex, and the main treatment methods for DR Include: panretinal laser photocoagulation therapy, pars plana vitrectomy and intravitreal injection of drugs, etc. However, all the treatment methods have certain limitations. In recent years, progress has been made in the fields of intravitreal injection of anti-vascular endothelial growth factor drugs, anti-inflammatory therapy, anti-oxidative stress injury drugs, neuroprotective drugs, gene therapy and stem cell therapy. DR treatment drugs are loaded with nanoparticles, hydrogels and photosensitive materials, which can be continuously and efficiently released in the eye, extending the time interval of administration. In the future, personalized and precise treatment based on biomarker detection can develop more accurate treatment plans for patients and improve curative effect.