ObjectiveTo summary the study results of the Sichuan Gastric Cancer Early Detection and Screening Research Program (SIGES). MethodsIn the past 10 years, SIGES program conducted a series of clinical and clinical epidemiological studies on the current situation and strategies of gastric cancer prevention and control in China, which provided evidence for supply-side structural reform to improve the gastric cancer prevention and control. We collected related studies and made a review. ResultsSIGES program systematically and specifically studied carcinogenic pathogens, risk factors, screening strategies, as well as critical technique and system construction of tertiary prevention for gastric cancer. The main results supported that Helicobacter pylori was highly correlated with precancerous atrophic gastritis and gastric cancer. Oncoviruses, such as Epstein-Barr virus, hepatitis B virus, human cytomegalovirus, human papillomavirus, John Cunningham virus were correlated with the risk of gastric cancer, and should be paid further attention in the prevention and screening strategy of gastric cancer. Ethnicity, domicile, and family history of gastric cancer were also correlated with gastric cancer and gastric cancer-related risk factors, so it was suggested to include in the personalized evaluation criteria system of high-risk groups for gastric cancer. ConclusionsAt present, the prevention and control of gastric cancer in China has achieved substantial achievements, but the burden of gastric cancer keeps heavy. It is still necessary to conduct further scientific research on critical technique or issues in designing prevention and control strategies.
Cancer prevention and control is an important healthcare task towards major diseases of the Chinese people and an important part of the “Healthy China 2030” plan outline. This article summarizes and introduces the current status and practical experience of subnational cancer prevention and treatment status in Yibin City and Ya’an City of Sichuan Province. Lung cancer, digestive system cancers, and cervical and breast cancers compose of the majority of cancers with high incidence. In the aspect of cancer epidemiology, there are certain disparities among cities and between urban and rural areas, among which the mortality risk of cancer in rural areas is higher. In Yibin and Ya’an cities, the specialized agencies and governance system for subnational cancer prevention and control are still in the early stage of development, and the background data such as cancer-specific survival rate, public awareness of core knowledge on cancer prevention and control, quality control of key techniques, and healthcare resources in subnational areas are still unclear. Therefore, all levels of cancer prevention and control need further strengthening the organizational leadership and system construction, and promoting the hierarchic healthcare and balanced development.