The therapeutic effects of panretinal cryotherapy(PRC)on proliferative diabetic retinopathy(PDR)were prospectively investigated in 80 eyes with PDR of 44 patients.Forty eyes with PDR(20 of them stage Ⅳ and 20 stage Ⅴ)received PRC operation.Of the 80 eyes,the other 40 ones with stage Ⅳ and Ⅴ similar to the formers were observed conservatively as controls.The follow up duration was 2 years.We found that in the cases of stage Ⅳ,no more remarkable visual loss was found after operation.There was a significant difference comparing with the control（P＜0.002）,and the retinal neovascularization regressed more noticeably than the control group（P＜0.001）.In the cases of stage Ⅴ,the incidence of the traction retinal detachment was 55% in the operated group,and was 20% in the control group.There was a statistic difference between them（P＜0.05）.The clearance of the vitreous hemorrhage was more rapid in the operated group than the control（P＜0.025）.The above results suggest that cryotherapy is suitable for the cases of earlier stage which cannot be performed with photocoagulation for any reasons,but not for the patients with advanced retinal proliferation.Photocoagulation for any reasons,but not for the patients with advanced retinal proliferation. （Chin J Ocul Fundus Dis,1993,9:148-151）
ObjectiveTo explore the prognostic risk factors for patients with gram positive coccus bloodstream infections. MethodsBy retrospective analysis, 93 patients with gram positive coccus bloodstream infections were recruited from the China-Japan Friendship Hospital during January 2013 to April 2015.According to the 28-day survival situation, the patients were divided into a survival group and a death group.The clinical data including basic diseases and invasive operation were collected.Logistic regression analysis was used to evaluate the risk factors for predicting prognosis. ResultsThe albumin concentration in the death group was lower than that in the survival group (P < 0.05).The D-Dimer concentration, APACHEⅡscores, the percentage of patients with mechanical ventilation, and the percentage of patients with deep venous cannels in the death group were all higher than those in the survival group (P < 0.05).The percentages with diabetes mellitus, surgery, tumor, renal failure in the patients with enterococcus bloodstream infections were much higher than those patients with other gram positive coccus bloodstream infections (P < 0.05), but were not different with those patients with Staphylococcus aureus bloodstream infection (P > 0.05).The APACHEⅡscore and albumin concentration had statistical significance for predicting the 28-day and 90-day mortality.The area under the receiver operating characteristic (ROC) curve was 0.768 and 0.775.If using APACHEⅡscore > 22.5 as cut off value for predicting death in 28 days, the sensitivity was 70.0%, and the specificity was 81.2%.If Using albumin concentration < 32.5 g/L as a cutoff value for predicting death in 28 days, the sensitivity was 55.3%, and the specificity was 86.7%. The logistic multifactor analysis revealed only the lower albumin concentration was an independent prognostic factor for 28-day mortality of the patients with gram positive coccus bloodstream infections (P < 0.05). ConclusionsThe patients with diabetes mellitus, surgery, tumor, and renal failure need to be cautious of enterococcus bloodstream infection.The low albumin concentration suggests a poor prognosis in patients with gram positive coccus bloodstream infections.