目的:总结胸腺类癌的临床表现、病理特征、CT表现及其临床价值。方法:对本院收治的2例胸腺类癌进行分析并结合文献复习。结果:胸腺类癌发病率低,大部分早期患者无临床症状,经胸部X线、CT检查时发现;中晚期始出现症状。病理检查出类癌后,电镜可见神经内分泌颗粒,免疫组化显示神经特异性烯醇化酶、肿瘤嗜铬蛋白A、促皮质素阳性。胸部CT表现特征为起于前上纵隔肿块,常位于心底部大血管和心包周围,肿块内密度不均,可见钙化,增强后轻中度强化,易发生胸内外转移。结论:胸腺类癌是一罕见的前纵隔肿瘤,根据CT特征,结合临床可有助诊断、指导手术、推测预后,因此CT在临床诊治中有非常重要的价值。
Citation:
WEN Xiaoling,DENG Kaihong.. The CT Diagnosis of Thymic Carcinoid and the Literature Review. West China Medical Journal, 2009, 24(2): 400-402. doi:
Copy
Copyright © the editorial department of West China Medical Journal of West China Medical Publisher. All rights reserved
1. |
Rosai J,Higa E.Mediastinal endocrine neoplasm of probable thymic origin,related to carcinoid tumor,clinicopathologic study of 8 cases[J].Cancer,1972,29(4):1061-1074..
|
2. |
Kulke MH,Mayer RJ.Carcinoid tumors[J].N Engl J Med,1999,340:8582-8681..
|
3. |
刘新兰,秦璟,刘明放,等.胸腺类癌的诊断与治疗1例及文献复习[J].宁夏医学杂志,2005,27(10):702-703..
|
4. |
Viebahn R,Hiddemann W,Klinke F,et al.Thymus carcinoid[J].Pathol Res Pract,1985,180(4):445-451..
|
5. |
Fukai I,Masaoka A,Fujii Y,et al.Thymic neuroendocrine tumor(thymic carcinoid):A clinicopathologic study in 15 patients[J].Ann Thorax Surg,1999,67(1):208211.Comment in:7-9..
|
6. |
邢焕英,张胜花,纪金梅.胸腺类癌1例[J].中国医学影像技术,2006,22(7):997..
|
7. |
韩丹,巫北海,宋光义.纵隔和胸腺类癌CT表现[J].放射学实践,2003,18(7):483-484.
|
- 1. Rosai J,Higa E.Mediastinal endocrine neoplasm of probable thymic origin,related to carcinoid tumor,clinicopathologic study of 8 cases[J].Cancer,1972,29(4):1061-1074..
- 2. Kulke MH,Mayer RJ.Carcinoid tumors[J].N Engl J Med,1999,340:8582-8681..
- 3. 刘新兰,秦璟,刘明放,等.胸腺类癌的诊断与治疗1例及文献复习[J].宁夏医学杂志,2005,27(10):702-703..
- 4. Viebahn R,Hiddemann W,Klinke F,et al.Thymus carcinoid[J].Pathol Res Pract,1985,180(4):445-451..
- 5. Fukai I,Masaoka A,Fujii Y,et al.Thymic neuroendocrine tumor(thymic carcinoid):A clinicopathologic study in 15 patients[J].Ann Thorax Surg,1999,67(1):208211.Comment in:7-9..
- 6. 邢焕英,张胜花,纪金梅.胸腺类癌1例[J].中国医学影像技术,2006,22(7):997..
- 7. 韩丹,巫北海,宋光义.纵隔和胸腺类癌CT表现[J].放射学实践,2003,18(7):483-484.