目的:分析小儿紫癜性肾炎的临床特点。方法:回顾分析两院儿科最近8年收治的小儿紫癜性肾炎180例的临床表现、实验室检查结果,治疗和预后等方面的资料。结果(1)临床以血尿蛋白尿型最多见(61/180),其次为急性肾炎型(36/180)、肾病综合征型(31/180)和单纯血尿或蛋白尿型(25/180)。(2)重症病儿短期使用激素可改善肾脏损害。(3)所有病例均有必要长期随访。结论:小儿紫癜性肾炎绝大多数预后良好,但病情反复不愈者可发展为终末期肾脏损害,故需要长期随访。
Citation:
LIU Ligang,ZHOU Taiguang,LU Changbi.. Clinical Analysis on 180 Children with Henoch-Schnlein Purpura Nephritis. West China Medical Journal, 2009, 24(2): 351-352. doi:
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- 1. 中华医学会儿科学会肾脏病学组.小儿肾小球疾病的临床分类,诊断及治疗[J].中华儿科杂志,2001,39(12):746-747..
- 2. Aalberse J,Dolman K,Ramnath G,et al.HenochSchnlein purpura in children:an epidemiological study among Dutch paediatricians on incidence and diagnostic criteria[J].Ann Rheum Dis,2007,66:1648-1650..
- 3. 叶红,高岩.儿童过敏性紫癜性肾炎的临床特点[J].广东医学,2003,24(11):1234-1235..
- 4. 季丽娜,陈大坤,曹力,等.儿童紫癜性肾炎临床病理研究(附65例分析)[J].中国实用儿科杂志,2008,23(6):422-424..
- 5. 张良,姜红.儿童过敏性紫癜肾炎的临床相关因素分析[J].中国实用儿科杂志,2008,23(6):456457..
- 6. 殷蕾,周纬,金燕粱,等.糖皮质激素对过敏性紫癜患儿肾损害预防作用的Meta分析[J].临床儿科杂志,2007,25(2):147-150..
- 7. Aaron L.Friedman.Which Children with Henoch Schenlein Purpura Nephritis Will Develop Renal Damage[J].AAP Grand Rounds,2005,13:63-64..
- 8. Butani L,Morgenstern BZ.Longterm outcome in children after HenochSchnlein purpura nephritis[J].Clin Pediatr(Phila),2007,46(6):505-511.