The Role of Nutritional Support in Adjuvant Therapy for Respiratory Failure_West China Medical Journal

Authors：

 YANYi , CHENNa , ZHANGEr-dong

Department of Nutrition, Teaching Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610072, P. R. China;

Corresponding author：

Keywords：

Respiratory failure; Nutritional support; Adjuvant therapy; Therapeutic effect

DOI：

10.7507/1002-0179.20140462

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Objective To explore the role of nutritional support in adjuvant therapy for respiratory failure. Methods We took 72 patients with respiratory failure who were treated in our hospital from August 2011 to January 2013 as the research objects. They were divided into two groups:control group and trial group, with 36 patients in each group. The division of the groups was in accordance with the state food and drug administration clinical trial institution ethics committee standard operating procedures. In the control group, 36 patients were provided with regular treatments according to their condition, like maintaining the respiratory tract unobstructed, oxygen therapy, mechanical ventilation and anti-infection. In the trial group, we offered nutritional support in addition to the normal treatment. Consecutive 20 days was a course of treatment. After four courses, we inspected and put down two groups' respective clinical features, and made a contrast of their treatment conditions. We analyzed the treatments through observational indexes including assessment of eutrophication, treatment efficiency, pulmonary function and arterial blood gases. Results Both groups had obvious therapeutic effects. The observational indexes in the trial group were better than those in the control group. The total effective rate was 91.7% in the trail group after treatment, significantly higher than that in the control group (66.7%) (χ²=8.692, P=0.003); the lung capacity, the ventilation flow ratio and arterial blood gas analysis values in the trial group was better than those in the control group. Conclusion The effect of the nutritional support for the respiratory failure treatment is much better than the regular treatment. The total effective rate is improved while the death rate is lower than before and the patients recover quickly.

Citation： YANYi, CHENNa, ZHANGEr-dong. The Role of Nutritional Support in Adjuvant Therapy for Respiratory Failure. West China Medical Journal, 2014, 29(8): 1508-1511. doi: 10.7507/1002-0179.20140462 Copy

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10.	陈燕, 李鸿霞, 拓宽前. 欧洲营养不良风险调查方法在COPD稳定期患者中的应用研究[J]. 新疆中医药, 2011, 29(6):3-4.
11.	杨倩, 张桂, 赵蓓蕾. 1例重度营养不良并发慢性呼吸衰竭患者的营养支持[J]. 医学研究生学报, 2011, 24(8):895-896.
12.	王建茹, 王越茹. 慢性肺源性心脏病合并呼吸衰竭的营养支持治疗[J]. 现代中西医结合杂志, 2013, 22(5):469-470, 553.
13.	刘新茹, 李立群, 刘飒. COPD合并呼吸衰竭应用无创通气时营养支持[J]. 临床肺科杂志, 2012, 17(6):1129-1137.
14.	王海英, 李玲玲. 不同营养支持治疗方式对呼吸衰竭患者临床疗效观察[J]. 广州医药, 2012, 43(3):18-20.
15.	乌日娜, 杨敬平. 机械通气患者营养支持应用探讨[J]. 临床肺科杂志, 2009, 14(11):1486-1487.
16.	闫文翠, 张雅芬, 马秀芬, 等. 营养支持治疗对老年COPD合并呼吸衰竭患者的影响[J]. 中国老年学杂志, 2013, 33(18):4436-4437.
17.	薛森海, 赵长海, 孙丽娟. 1例重症甲型H1N1流感并发呼吸衰竭病人的营养支持[J]. 肠外与肠内营养, 2011, 18(1):42-45.
18.	徐丽丹, 赖小燕. 静脉营养支持疗法治疗COPD合并呼吸衰竭70例疗效分析[J]. 临床肺科杂志, 2010, 15(5):667-668.

1. 杨省振. 营养支持治疗慢性阻塞肺病并Ⅱ型呼吸衰竭疗效观察[J]. 临床心身疾病杂志, 2008, 14(4):365-365.
2. 陆再英, 钟南山. 内科学[M]. 7版. 北京:人民卫生出版社, 2008:109-114.
3. 熊宁宁, 刘芳, 蒋萌, 等. 临床试验机构伦理委员会标准操作规程[J]. 中国临床药理学与治疗学, 2003, 8(4):477-480.
4. 袁健红. 营养支持治疗慢性阻塞性肺病并Ⅱ型呼吸衰竭的临床疗效分析[J]. 中国医药指南, 2012, 10(35):541-542.
5. 杜岭先. 慢性阻塞性肺疾病合并呼吸衰竭的临床治疗与分析[J]. 中国医药指南, 2013, 11(19):557-557, 558.
6. 王传湄, 徐丽丹, 赖小燕. 营养支持治疗对COPD合并呼吸衰竭的影响[J]. 临床肺科杂志, 2009, 14(12):1591-1592.
7. Colombo S, Zangrillo A. Invasive and non-invasive ventilation in the treatment of acute respiratory failure[J]. G Ital Cardiol (Rome), 2010, 11(1):12-19.
8. 吕红, 黄建安. AECOPD合并呼吸衰竭营养支持治疗的临床观察[J]. 临床肺科杂志, 2013, 18(4):610-611.
9. 张爱华. 呼吸衰竭患者无创通气治疗的效果观察[J]. 中国医药指南, 2013, 11(34):94-95.
10. 陈燕, 李鸿霞, 拓宽前. 欧洲营养不良风险调查方法在COPD稳定期患者中的应用研究[J]. 新疆中医药, 2011, 29(6):3-4.
11. 杨倩, 张桂, 赵蓓蕾. 1例重度营养不良并发慢性呼吸衰竭患者的营养支持[J]. 医学研究生学报, 2011, 24(8):895-896.
12. 王建茹, 王越茹. 慢性肺源性心脏病合并呼吸衰竭的营养支持治疗[J]. 现代中西医结合杂志, 2013, 22(5):469-470, 553.
13. 刘新茹, 李立群, 刘飒. COPD合并呼吸衰竭应用无创通气时营养支持[J]. 临床肺科杂志, 2012, 17(6):1129-1137.
14. 王海英, 李玲玲. 不同营养支持治疗方式对呼吸衰竭患者临床疗效观察[J]. 广州医药, 2012, 43(3):18-20.
15. 乌日娜, 杨敬平. 机械通气患者营养支持应用探讨[J]. 临床肺科杂志, 2009, 14(11):1486-1487.
16. 闫文翠, 张雅芬, 马秀芬, 等. 营养支持治疗对老年COPD合并呼吸衰竭患者的影响[J]. 中国老年学杂志, 2013, 33(18):4436-4437.
17. 薛森海, 赵长海, 孙丽娟. 1例重症甲型H1N1流感并发呼吸衰竭病人的营养支持[J]. 肠外与肠内营养, 2011, 18(1):42-45.
18. 徐丽丹, 赖小燕. 静脉营养支持疗法治疗COPD合并呼吸衰竭70例疗效分析[J]. 临床肺科杂志, 2010, 15(5):667-668.

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West China Medical Journal

The Role of Nutritional Support in Adjuvant Therapy for Respiratory Failure

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